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Cause histamine release, so greater side effects comparing with Atracurium; Rarely used Atracurium: Safer alternative to tubocurarine with less side effects; Surgical anaesthetic & intubation facilitate endotracheal intubation and provide skeletal muscle relaxation to reduce the risk of laryngeal injury. [12]
Metaxalone, sold under the brand name Skelaxin, is a muscle relaxant medication used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. [1] Its exact mechanism of action is not known, but it may be due to general central nervous system depression . [ 1 ]
A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms , pain , and hyperreflexia . The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics .
Mephenoxalone (trade names Dorsiflex, Moderamin, Control-OM) is a muscle relaxant [2] and mild anxiolytic. [3] It inhibits neuron transmission, relaxing skeletal muscles by inhibiting the reflex arc. [citation needed] As the effect of muscle relaxation, mephenoxalone affects mental condition, and is also a treatment for nervousness and anxiety.
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.
Adverse effects occur in fewer than 1% of patients and include muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia, and dry mouth. All effects are reversible. [3] [4] Allergic reactions occur in fewer than 0.1% of patient and include skin rash, hives, Quincke's edema, and in some cases anaphylactic shock. [3] [7] [8] [9]
Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. [5] Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. [5] It is unclear if use in pregnancy and breastfeeding is safe. [6] It is an α 2-adrenergic agonist, but how it works is not entirely clear. [5]
Quaternary ammonium muscle relaxants are quaternary ammonium salts used as drugs for muscle relaxation, most commonly in anesthesia. It is necessary to prevent spontaneous movement of muscle during surgical operations. Muscle relaxants inhibit neuron transmission to muscle by blocking the nicotinic acetylcholine receptor. What they have in ...