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Unlike the other twelve vitamins, vitamin D is only conditionally essential - in a preindustrial society people had adequate exposure to sunlight and the vitamin was a hormone, as the primary natural source of vitamin D was the synthesis of cholecalciferol in the lower layers of the skin’s epidermis, triggered by a photochemical reaction with ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Calcifediol is the precursor for calcitriol, the active form of vitamin D. [3] [4] It is synthesized in the liver, by hydroxylation of cholecalciferol (vitamin D 3) at the 25-position. [3] This enzymatic 25-hydroxylase reaction is mostly due to the actions of CYP2R1 , present in microsomes , although other enzymes such as mitochondrial CYP27A1 ...
Metamorphic rocks are formed by subjecting any rock type—sedimentary rock, igneous rock or another older metamorphic rock—to different temperature and pressure conditions than those in which the original rock was formed. This process is called metamorphism, meaning to "change in form". The result is a profound change in physical properties ...
$9.95 at Amazon. Vitamin Code Raw D3. This once-daily formula contains 5,000 IU of fat-soluble vitamin D3. “What I love about Garden of Life is that it also has probiotics mixed in, so you get a ...
Metamorphic rocks once existed as igneous or sedimentary rocks, but have been subjected to varying degrees of pressure and heat within the Earth's crust. The processes involved will change the composition and fabric of the rock and their original nature is often hard to distinguish. Metamorphic rocks are typically found in areas of mountain ...
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