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Dogs with primary hypothyroidism also have increased levels of growth hormone and IGF-1; however, thyroxine and thyroid stimulating hormone levels are normal in dogs with hypersomatotropism. [1] Progestogens administered to dogs may result in endogenous adrenocorticotropic hormone secretion being suppressed, which lowers the cortisol ...
Treatment of hepatomegaly varies with the cause, so accurate diagnosis is the first concern. In auto-immune liver disease, prednisone and azathioprine may be used for treatment. [3] In lymphoma the treatment options include single-agent (or multi-agent) chemotherapy and regional radiotherapy, and surgery is an option in specific situations.
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Dogs are ten times more likely to be infected than humans. The disease in dogs can affect the eyes, brain, lungs, skin, or bones. [15] Histoplasmosis* is a fungal disease caused by Histoplasma capsulatum that affects both dogs and humans. The disease in dogs usually affects the lungs and small intestine. [16]
Liver showing chronic passive congestion associated with tricuspid valve incompetence. So called 'nutmeg liver', Split nutmeg, for those who have never seen this appearance.
Physical symptoms generally include coarse or rough facial features (including a flat nasal bridge, thick lips, and enlarged mouth and tongue), short stature with disproportionately short trunk , dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver (hepatomegaly) or spleen ...
Symptoms of early infantile GM1 (the most severe subtype, with onset shortly after birth) may include neurodegeneration, seizures, liver enlargement (hepatomegaly), spleen enlargement (splenomegaly), coarsening of facial features, skeletal irregularities, joint stiffness, distended abdomen, muscle weakness, exaggerated startle response to sound, and problems with gait.
Echinococcus granulosus, also called the hydatid worm or dog tapeworm, is a cyclophyllid cestode that dwells in the small intestine of canids as an adult, but which has important intermediate hosts such as livestock and humans, where it causes cystic echinococcosis, also known as hydatid disease.
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