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The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.
Several classes of medications, collectively referred to as antihypertensive medications, are available for treating hypertension. Use should take into account the person's cardiovascular risk (including risk of myocardial infarction and stroke), as well as blood pressure readings, in order to gain a more accurate picture of the person's risks.
Aliskiren, an orally active non-peptide renin inhibitor, was the first drug in its class on the market. It is used to treat hypertension as monotherapy or in combination with other antihypertensive agents. [7] [39] The key to the discovery of aliskiren was crystallography and molecular modeling techniques. Now, a solution has been found to the ...
ACE inhibitors dosages for hypertension Dosage Note: bid = two times a day, tid = three times a day, d = daily Drug dosages from Drug Lookup, Epocrates Online. Name Equivalent daily dose Start Usual Maximum Benazepril: 10 mg: 10 mg: 20–40 mg: 80 mg Captopril: 50 mg (25 mg bid) 12.5–25 mg bid-tid: 25–50 mg bid-tid: 150 mg/d Enalapril: 5 mg ...
This class of drugs is usually well tolerated. Common adverse drug reactions (ADRs) include: dizziness, headache, and/or hyperkalemia.Infrequent ADRs associated with therapy include: first dose orthostatic hypotension, rash, diarrhea, dyspepsia, abnormal liver function, muscle cramp, myalgia, back pain, insomnia, decreased hemoglobin levels, renal impairment, pharyngitis, and/or nasal ...
Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. [3] This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. [3]
Indications can impact the pricing of medications through Value-based Pricing, also known as indication specific pricing or indication value-based pricing. [ 15 ] [ 16 ] Since drugs can be used for different indications, this form of pricing would set different prices for each indication based on the value the drug offers for whatever it is ...
Hydralazine is often used to treat hypertension in pregnancy, though, with either labetalol and/or methyldopa. [11] Hydralazine is commonly used in combination with isosorbide dinitrate for the treatment of congestive heart failure in black populations. This preparation, isosorbide dinitrate/hydralazine, was the first race-based prescription ...