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Toxic vacuolization. A vacuolated neutrophil. Specialty. Hematology. Causes. Sepsis, bacterial infection, alcohol toxicity, liver failure, G-CSF treatment. Toxic vacuolation, also known as toxic vacuolization, [1] is the formation of vacuoles in the cytoplasm of neutrophils in response to severe infections or inflammatory conditions. [2][3]
Some drugs, such as prednisone, have the same effect as cortisol and adrenaline (epinephrine), causing marginated neutrophils to enter the blood stream. Overdoses of some drugs can cause very high levels of neutrophils in the blood. [citation needed] There is a single case report of severe neutrophilia with bupropion overdose. [3]
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Neutropenia. Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood. [4] Neutrophils make up the majority of circulating white blood cells and serve as the primary defense against infections by destroying bacteria, bacterial fragments and immunoglobulin -bound viruses in the blood. [5]
Dermatology. Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, [1][2] is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
Stay hydrated. The flu can cause a fever, which can increase the odds of sweating. Replacing those fluids is important to keep your body functioning as best as possible while you’re sick, Dr ...
Leukopenia. Leukopenia (from Greek λευκός (leukos) 'white' and πενία (penia) 'deficiency') is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body's primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection.
Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, also sends Crohn's disease into clinical remission, new findings suggest.