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β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
HMB, or hydroxymethylbutyrate, is being touted online as a muscle building supplement. Dietitians explain what HMB is, its health benefits, and risks.
The inhibition of exercise-induced skeletal muscle damage by HMB is affected by the time that it is used relative to exercise. [29] [33] The greatest reduction in skeletal muscle damage from a single bout of exercise appears to occur when calcium HMB is ingested 1–2 hours prior to exercise. [33]
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β-Hydroxy β-methylbutyryl-coenzyme A (HMB-CoA), also known as 3-hydroxyisovaleryl-CoA, is a metabolite of L-leucine that is produced in the human body. [1] [2] Its immediate precursors are β-hydroxy β-methylbutyric acid (HMB) and β-methylcrotonoyl-CoA (MC-CoA). It can be metabolized into HMB, MC-CoA, and HMG-CoA in humans.
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HMB may refer to: Compounds. β-Hydroxy β-methylbutyric acid, (CH 3) 2 C(OH)CH 2 COOH, a metabolite of the essential amino acid leucine, synthesized in the human body;
A registered dietician discusses the harmful myths about nutrition that wellness culture has tricked us into believing. I'm a dietitian. These 5 myths about nutrition are actually hurting your health
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