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Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
In a recently released report, the CDC estimates that nearly half a million Americans suffer from alpha-gal syndrome.This potentially life-threatening allergy to red meat is triggered by tick ...
Here’s everything you need to know about alpha-gal syndrome
What is alpha-gal syndrome? The lone star tick can cause an allergic reaction known as alpha-gal syndrome. The tick's saliva contains a sugar molecule called galactose-alpha-1,3-galactose (alpha-gal).
Alpha-gal allergy - Alpha-gal syndrome is likely caused by a hypersensitivity reaction to the Alpha-gal (Galactose-alpha-1,3-galactose) sugar molecule introduced by ticks while feeding on a human host. The immune reaction can leave people with an allergy to red meat and other mammalian derived products.
Life expectancy with Fabry disease for males was 58.2 years, compared with 74.7 years in the general population, and for females 75.4 years compared with 80.0 years in the general population, according to registry data from 2001 to 2008. The most common cause of death was cardiovascular disease, and most of those had received kidney replacements.
Serious and potentially life-threatening symptoms occur after people eat red meat or are exposed to other products containing the alpha-gal molecule, the CDC said. Alpha-gal syndrome symptoms
When the same tick attaches to the next host (e.g., a human) it transfers the alpha-gal to the tissues of that next host. The immune system of some humans recognises alpha-gal as foreign and so produces antibodies against it. In this case the antibody produced is IgE, which is the type of antibody responsible for most allergic reactions.