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2. Phase-contrast microscopy - Wikipedia

   en.wikipedia.org/wiki/Phase-contrast_microscopy

   The success of the phase-contrast microscope has led to a number of subsequent phase-imaging methods. In 1952, Georges Nomarski patented what is today known as differential interference contrast (DIC) microscopy. [8] It enhances contrast by creating artificial shadows, as if the object is illuminated from the side.

3. Differential interference contrast microscopy - Wikipedia

   en.wikipedia.org/wiki/Differential_interference...

   Micrasterias furcata imaged in transmitted DIC microscopy Laser-induced optical damage in LiNbO 3 under 150× Nomarski microscopy. Differential interference contrast (DIC) microscopy, also known as Nomarski interference contrast (NIC) or Nomarski microscopy, is an optical microscopy technique used to enhance the contrast in unstained, transparent samples.

4. Phase-contrast imaging - Wikipedia

   en.wikipedia.org/wiki/Phase-contrast_imaging

   Phase-contrast imaging is the highest resolution imaging technique ever developed, and can allow for resolutions of less than one angstrom (less than 0.1 nanometres). It thus enables the direct viewing of columns of atoms in a crystalline material. [20] [21] The interpretation of phase-contrast images is not a straightforward task.

5. Condenser (optics) - Wikipedia

   en.wikipedia.org/wiki/Condenser_(optics)

   Many older microscopes house these elements in a turret-type condenser, these elements are housed in a turret below the condenser lens and rotated into place. Specialised condensers are also used as part of Differential Interference Contrast and Hoffman Modulation Contrast systems, which aim to improve contrast and visibility of transparent ...

6. Microscopy - Wikipedia

   en.wikipedia.org/wiki/Microscopy

   Antonie van Leeuwenhoek (1632–1723). The field of microscopy (optical microscopy) dates back to at least the 17th-century.Earlier microscopes, single lens magnifying glasses with limited magnification, date at least as far back as the wide spread use of lenses in eyeglasses in the 13th century [2] but more advanced compound microscopes first appeared in Europe around 1620 [3] [4] The ...

7. Contrast transfer function - Wikipedia

   en.wikipedia.org/wiki/Contrast_transfer_function

   The effect of the contrast transfer function can be seen in the alternating light and dark rings (Thon rings), which show the relation between contrast and spatial frequency. The contrast transfer function (CTF) mathematically describes how aberrations in a transmission electron microscope (TEM) modify the image of a sample.

8. Quantitative phase-contrast microscopy - Wikipedia

   en.wikipedia.org/wiki/Quantitative_phase...

   Such objects do, however, induce a phase shift that can be observed using a phase contrast microscope. Conventional phase contrast microscopy and related methods, such as differential interference contrast microscopy, visualize phase shifts by transforming phase shift gradients into intensity variations. These intensity variations are mixed ...

9. Interference reflection microscopy - Wikipedia

   en.wikipedia.org/wiki/Interference_reflection...

   Interference reflection microscopy (IRM), also called Reflection Interference Contrast Microscopy (RICM) or Reflection Contrast Microscopy (RCM) depending on the specific optical elements used, is an optical microscopy technique that leverages thin-film interference effects to form an image of an object on a glass surface.