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  2. Diazepam - Wikipedia

    en.wikipedia.org/wiki/Diazepam

    The elimination half-life of diazepam and also the active metabolite desmethyldiazepam increases significantly in the elderly, which may result in prolonged action, as well as accumulation of the drug during repeated administration. [113]

  3. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    It is fairly important to note that elimination half-life of diazepam and chlordiazepoxide, as well as other long half-life benzodiazepines, is twice as long in the elderly compared to younger individuals.

  4. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    The elimination half-life of diazepam and chlordiazepoxide, as well as other long half-life benzodiazepines, is twice as long in the elderly compared to younger individuals. Many doctors do not adjust benzodiazepine dosage according to age in elderly patients. [137]

  5. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Long-acting compounds have a half-life of 40–250 hours. They have a risk of accumulation in the elderly and in individuals with severely impaired liver function, but they have a reduced severity of rebound effects and withdrawal. Examples are diazepam, clorazepate, chlordiazepoxide, and flurazepam.

  6. Temazepam - Wikipedia

    en.wikipedia.org/wiki/Temazepam

    Elimination half-life: 8–20 hours: Duration of action: ... Benzodiazepines also require special caution if used in the elderly, ... diazepam, and alcohol, was a ...

  7. Celine Dion Took Potentially Fatal Dosages of Valium to Cope ...

    www.aol.com/celine-dion-took-potentially-fatal...

    Celine Dion Took Potentially Fatal Dosages of Valium to Cope With Symptoms of Stiff Person Syndrome: ‘I Did Not Know Honestly That It Could Kill Me’ Steven J. Horowitz June 11, 2024 at 11:05 PM

  8. Celine Dion Recalls Taking Up to 90 Milligrams of Valium Amid ...

    www.aol.com/entertainment/celine-dion-recalls...

    Celine Dion is getting candid about her health. In an interview with Hoda Kotb on Tuesday -- portions of which aired on the Today show ahead of the scheduled primetime special -- the 56-year-old ...

  9. Chlordiazepoxide - Wikipedia

    en.wikipedia.org/wiki/Chlordiazepoxide

    The half-life of chlordiazepoxide is from 5 to 30 hours but has an active benzodiazepine metabolite, nordiazepam, which has a half-life of 36 to 200 hours. [31] The half-life of chlordiazepoxide increases significantly in the elderly, which may result in prolonged action as well as accumulation of the drug during repeated administration.