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Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .
Anticonvulsant racetams, including levetiracetam, brivaracetam, and seletracetam, act as synaptic vesicle glycoprotein 2A (SV2A) ligands. [6] A newer analogue of these agents, padsevonil , is no longer a racetam itself but is much more potent in comparison and interacts with not only SV2A but also synaptic vesicle glycoprotein 2B (SV2B) and ...
The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study showed that most blood concentrations in breastfed infants of mothers taking carbamazepine, oxcarbazepine, valproate, levetiracetam, and topiramate were quite low, especially in relationship to the mother's level and what the fetal level would have been ...
Other drugs for epilepsy — like oxcarbazepine, lamotrigine or levetiracetam — may actually improve function in people with intimate-related symptoms.
64051 Ensembl ENSG00000159164 ENSMUSG00000038486 UniProt Q7L0J3 Q9JIS5 RefSeq (mRNA) NM_014849 NM_001278719 NM_001328674 NM_001328675 NM_022030 RefSeq (protein) NP_001265648 NP_001315603 NP_001315604 NP_055664 NP_071313 Location (UCSC) Chr 1: 149.9 – 149.92 Mb Chr 3: 96.09 – 96.1 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Synaptic vesicle glycoprotein 2A (SV2A) is a ...
The study does present with limitations. First, it was conducted in Sweden, meaning there may be a need for more diversity with later studies and that the results cannot be generalized to all ...
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[150] [151] Controlled release carbamazepine appears to work as well as immediate release carbamazepine, and may have fewer side effects. [152] [153] In the United Kingdom, carbamazepine or lamotrigine are recommended as first-line treatment for focal seizures, with levetiracetam and valproate as second-line due to issues of cost and side effects.