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[3] [4] Methylprednisolone succinate is provided as two different salts when used as a pharmaceutical drug: a sodium salt (methylprednisolone sodium succinate; brand name Solu-Medrol, others) and a hydrogen salt (methylprednisolone hemisuccinate or methylprednisolone hydrogen succinate; brand name Urbason). [3] [4]
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
[23] [22] Depo-Medrol is additionally approved for intralesional, intra-articular, and soft tissue injections. Depo-Medrol is available as sterile aqueous solution in 20 mg/mL, 40 mg/mL, or 80 mg/mL strengths. [23] Solu-Medrol is the only derivative of methylprednisolone that is approved for intravenous infusion, as the sterile powder is ...
375 mg/m 2: IV infusion: Day 0 Etoposide: 40 mg/m 2: IV infusion over 1 hr: Days 1-4 Solu-Medrol - Methylprednisolone: 500 mg: IV bolus over 15 min: Days 1-5 High-dose Ara-C — cytarabine: 2000 mg/m 2: IV infusion over 2 hrs: Day 5 Platinol (cisplatin) 25 mg/m 2: IV continuous infusion over 24 hrs: Days 1-4
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Prednisolone is used in the treatment of inflammatory and allergic conditions in cats, dogs, horses, small mammals such as ferrets, birds, and reptiles. [ 57 ] [ 58 ] Its usage in treating inflammation, immune-mediated disease, Addison's disease , and neoplasia is often considered off-label use.
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