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Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. [1] Signs and symptoms may include vomiting , abdominal pain , deep gasping breathing , increased urination , weakness, confusion and occasionally loss of consciousness . [ 1 ]
[8] proper treatment usually results in full recovery, though death can result from inadequate or delayed treatment, or from complications (e.g., brain edema). [12] Preventing DKA is attainable by following some precautions. [16] While feeling unwell, Start with regular monitoring of blood glucose levels.
Treatment depends on the underlying cause of the ketoacidosis. Diabetic ketoacidosis is resolved with insulin infusion, intravenous fluids, electrolyte replacement and supportive care. [1] Alcoholic ketoacidosis is treated with intravenous dextrose and supportive care and usually does not require insulin. [2]
DKA is a serious complication which is particularly common in children under five years of age and can lead to cerebral edema, coma, and death. [9] A 2013 publication also stated that children who develop T1D while enrolled in TEDDY are diagnosed sooner after the onset of the disease than those not in the study.
Intravenous sodium bicarbonate is indicated in the treatment of metabolic acidosis, such as can occur in severe kidney disease, diabetic ketoacidosis [citation needed], circulatory insufficiency, extracorporeal circulation of blood, in hemolysis requiring alkalinization of the urine to avoid nephrotoxicity of blood pigments, and certain drug intoxications, such as by barbiturate overdose ...
This suggests that it may be important to target mood in treatment. In the case of children and young people, especially if they are socially disadvantaged, research suggests that it is important that healthcare providers listen to and discuss their feelings and life situation to help them engage with diabetes services and self-management. [69 ...
Alanine is a direct precursor in gluconeogenesis and can be used for treatment of ketotic hypoglycemia. If an episode begins, affected children should be given fluids and carbohydrate-rich foods immediately, if swallowing is not compromised. [2] A carbohydrate gel can be applied to the inside of the mouth in children who are unable to swallow.
Some children also have high levels of ketones in the blood and urine, or signs of metabolic acidosis. [5] Permanent neonatal diabetes starts slightly later, typicalaly around six weeks of age. Regardless of type, preterm infants tend to experience symptoms earlier, typically around one week of age. [6]