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GcMAF (or Gc protein-derived macrophage activating factor) is a protein produced by modification of vitamin D-binding protein. [1] It has been falsely promoted as a treatment for various medical conditions, but claims of its benefits are not supported by evidence.
While serum low 25-hydroxyvitamin D status has been associated with a higher risk of cancer in observational studies, [85] [86] [87] the general conclusion is that there is insufficient evidence for an effect of vitamin D supplementation on the risk of cancer, [2] [88] [89] although there is some evidence for reduction in cancer mortality.
1α-Hydroxyvitamin D 5 is a chemical derivative of vitamin D 5.The motive to study 1α-hydroxyvitamin D 5 as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis.
A review of clinical trials in the treatment of colds with small and large doses of Vitamin C has established that there is no evidence that it decreases the incidence of common colds. [28] After 33 years of research, it is still not established whether vitamin C can be used as a treatment for cancer. [29]
The U.S. Preventive Services Task Force say vitamin D supplements do not reduce the risk of falls or bone fractures in healthy older adults. The draft recommendation notes vitamin D can be helpful ...
It transports vitamin D metabolites between skin, liver and kidney, and then on to the various target tissues. [6] [9] As Gc protein-derived macrophage activating factor it is a Macrophage Activating Factor (MAF) that has been tested for use as a cancer treatment that would activate macrophages against cancer cells. [10]
Pancreatic Cancer Patient Survival Doubled With High Dose Of Common Vitamin, Study Finds. ... Breast cancer was the only type for which treatment advances prevented more deaths.
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
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