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The sequential probability ratio test (SPRT) is a specific sequential hypothesis test, developed by Abraham Wald [1] and later proven to be optimal by Wald and Jacob Wolfowitz. [2] Neyman and Pearson's 1933 result inspired Wald to reformulate it as a sequential analysis problem.
Medical calculators arose because modern medicine makes frequent use of scores and indices that put physicians' memory and calculation skills to the test. [2] The advent of personal computers, the Internet and Web, and more recently personal digital assistants (PDAs) have formed an environment conducive to their development, spread and use.
In mathematics, the Weierstrass M-test is a test for determining whether an infinite series of functions converges uniformly and absolutely. It applies to series whose terms are bounded functions with real or complex values, and is analogous to the comparison test for determining the convergence of series of real or complex numbers.
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MDCalc is a free online medical reference for healthcare professionals that provides point-of-care clinical decision-support tools, including medical calculators, scoring systems, and algorithms. [1]
In clinical practice, post-test probabilities are often just estimated or even guessed. This is usually acceptable in the finding of a pathognomonic sign or symptom, in which case it is almost certain that the target condition is present; or in the absence of finding a sine qua non sign or symptom, in which case it is almost certain that the target condition is absent.
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