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  2. 5α-Reductase 2 deficiency - Wikipedia

    en.wikipedia.org/wiki/5α-Reductase_2_deficiency

    Two of three isozymes of 5αR can catalyze the transformation of T to DHT, but it is only 5αR2D that causes 46XY, DSD. 5αR2 is encoded by the gene SRD5A2 which is located on the short arm of chromosome 2 and contains five exons and four introns. 5αR2 consists of 254 amino acid residues with reported mutations at 67 of them with multiple different mutations at some residues.

  3. Aromatase excess syndrome - Wikipedia

    en.wikipedia.org/wiki/Aromatase_excess_syndrome

    Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.

  4. Dihydrotestosterone - Wikipedia

    en.wikipedia.org/wiki/Dihydrotestosterone

    In the case of women, mean circulating DHT levels have been found to be about 9 ng/dL (0.3 nmol/L) in premenopausal women and 3 ng/dL (0.1 nmol/L) in postmenopausal women. [5] There was no variation in DHT levels across the menstrual cycle in premenopausal women, which is in contrast to testosterone (which shows a peak at mid-cycle). [5]

  5. Is It Just Stress...Or Perimenopause? Doctors Explain ... - AOL

    www.aol.com/just-stress-perimenopause-doctors...

    This sudden rise in body temperature affects an estimated 35 to 50 percent of perimenopausal women, according to Harvard Health. Again, the severity will differ from woman to woman—some may feel ...

  6. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...

  7. Androgen replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Androgen_replacement_therapy

    Androgen deficiencies in women have also, as of 2001, been recognized as a medical disorder that can be treated with ART. [8] As with men, symptoms associated with androgen deficiency are most prevalent with age, and androgen replacement therapy has been shown to help with symptoms of menopause .

  8. 5 symptoms men over 40 should never ignore - AOL

    www.aol.com/finance/5-symptoms-men-over-40...

    Research shows men are more likely than women to avoid—or delay—necessary medical care, even when their symptoms disrupt their lives or become chronic. An online survey conducted by the ...

  9. Late-onset hypogonadism - Wikipedia

    en.wikipedia.org/wiki/Late-onset_hypogonadism

    As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...

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