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  2. Adrenal gland - Wikipedia

    en.wikipedia.org/wiki/Adrenal_gland

    Adrenal glands, anterior (left) and posterior (right) surface. The adrenal glands are located on both sides of the body in the retroperitoneum, above and slightly medial to the kidneys. In humans, the right adrenal gland is pyramidal in shape, whereas the left is semilunar or crescent shaped and somewhat larger. [8]

  3. Zona fasciculata - Wikipedia

    en.wikipedia.org/wiki/Zona_fasciculata

    Steroid-producing adrenal tumours and hyperplasia of the zona fasciculata result in excess cortisol production and are the cause for adrenal Cushing's syndrome. [1] The genetic disorder McCune–Albright syndrome can also present as Cushing's syndrome in affected patients. Adrenal gland (zona fasciculata layer).

  4. Adrenal cortex - Wikipedia

    en.wikipedia.org/wiki/Adrenal_cortex

    The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. [2]

  5. Endocrine system - Wikipedia

    en.wikipedia.org/wiki/Endocrine_system

    Cushing's disease and Addison's disease are pathologies involving the dysfunction of the adrenal gland. Dysfunction in the adrenal gland could be due to primary or secondary factors and can result in hypercortisolism or hypocortisolism. Cushing's disease is characterized by the hypersecretion of the adrenocorticotropic hormone (ACTH) due to a ...

  6. Zona reticularis - Wikipedia

    en.wikipedia.org/wiki/Zona_reticularis

    The zona reticularis (sometimes, reticulate zone) is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance (L. reticulum - net).

  7. Zona glomerulosa - Wikipedia

    en.wikipedia.org/wiki/Zona_glomerulosa

    H & E staining of the adrenal cortex. The zona glomerulosa is the outermost layer, below the renal capsule (near the pointer) In response to increased potassium levels, renin or decreased blood flow to the kidneys , cells of the zona glomerulosa produce and secrete the mineralocorticoid aldosterone into the blood as part of the renin ...

  8. Sympathoadrenal system - Wikipedia

    en.wikipedia.org/wiki/Sympathoadrenal_system

    Electrical impulses carried by the sympathetic nervous system are converted to a chemical response in the adrenal gland. Chromaffin cells contained in the adrenal medulla act as postganglionic nerve fibers that release this chemical response into the blood as a circulating messenger. The sympathoadrenal system can activate and discharge ...

  9. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    In humans and other animals, the adrenocortical hormones are hormones produced by the adrenal cortex, the outer region of the adrenal gland.These polycyclic steroid hormones have a variety of roles that are crucial for the body's response to stress (for example, the fight-or-flight response), and they also regulate other functions in the body.