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It does so in a time-dependent rather than dose-dependent manner, meaning that risk can be minimized by reducing the duration of use. [25] Amikacin causes nephrotoxicity (damage to the kidneys), by acting on the proximal renal tubules.
Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when taken orally as the stomach will digest the drug before it goes into the ...
Streptomycin. 2D line-angle representation.. Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside ().
There are numerous variables that influence the interpretation of drug concentration data: time, route and dose of drug given, time of blood sampling, handling and storage conditions, precision and accuracy of the analytical method, validity of pharmacokinetic models and assumptions, co-medications and, last but not least, clinical status of ...
In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is ...
Olena Ruban/Getty Images. 4. Incompatible: Taurus and Aquarius. The zodiac’s bull is stable and predictable, especially in matters of the heart.That can spell romance and reliability for some ...
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In clinical pharmacology, dose refers to the amount of drug administered to a person, and dosage is a fuller description that includes not only the dose (e.g., "500 mg") but also the frequency and duration of the treatment (e.g., "twice a day for one week"). Exposure means the time-dependent concentration (often in the circulatory blood or ...
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related to: amikacin one time dose- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Working to be "the most powerful patient advocate in America" - Forbes