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2. Cimetidine - Wikipedia

   en.wikipedia.org/wiki/Cimetidine

   Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [ 1 ] [ 9 ] [ 10 ] It is mainly used in the treatment of heartburn and peptic ulcers .

3. Famotidine - Wikipedia

   en.wikipedia.org/wiki/Famotidine

   Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within an ...

4. H2 receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/H2_receptor_antagonist

   Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

5. Drugs for acid-related disorders - Wikipedia

   en.wikipedia.org/wiki/Drugs_for_acid-related...

   There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.

6. Antihistamine - Wikipedia

   en.wikipedia.org/wiki/Antihistamine

   Normally, histamine acts on H 2 to stimulate acid secretion; drugs that inhibit H 2 signaling thus reduce the secretion of gastric acid. H 2-antihistamines are among first-line therapy to treat gastrointestinal conditions including peptic ulcers and gastroesophageal reflux disease. Some formulations are available over the counter.

7. Drugs in pregnancy - Wikipedia

   en.wikipedia.org/wiki/Drugs_in_pregnancy

   Heartburn is a common symptom of late term pregnancy during which up to 80% of pregnant women have experienced it by the end of their third trimester. [12] Heartburn often indicates the development of gastro-esophageal reflux disease (GERD), where the lower esophageal sphincter relaxes due to elevated progesterone levels causing increased ...