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Originally, adrenosterone was called Reichstein's substance G. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone. [2] Adrenosterone is sold as a dietary supplement since 2007 as a fat loss and muscle gaining supplement.
11-Oxomogroside A 1; Mogroside III A 2; 11-Deoxymogroside III; 11-Oxomogroside IV A; Mogroside V; 7-Oxomogroside V; 11-Oxo-mogroside V; Mogroside VI; Siamenoside I; The total content of mogrosides in Siraitia grosvenorii fruit is 3.8% with Mogroside V having the highest content (0.8% to 1.3% w/w). [3]
11-Ketotestosterone (11-KT) is an oxidized form of testosterone that contains a keto group at the C11 position. It is related to adrenosterone , an androgen found in trace quantities in humans. In fish , 11-ketotestosterone functions as the endogenous androgenic sex hormone.
HSD-11β Type 1 is responsible for converting cortisone to cortisol by acting as an oxo-reductase because it is NADP(H) dependent, while HSD-11β Type 2 inactivates cortisol to cortisone via NAD. [ 9 ] 10-d hyperlipidemia increases the HSD-11β Type 1 expression in visceral and subcutaneous adipose tissues. [ 9 ]
Beta-amyrin 11-oxidase (EC 1.14.13.134, CYP88D6) is an enzyme with systematic name beta-amyrin,NADPH:oxygen oxidoreductase (hydroxylating). [1] This enzyme catalyses the following chemical reaction beta-amyrin + 2 O 2 + 2 NADPH + 2 H + ⇌ {\displaystyle \rightleftharpoons } 11-oxo-beta-amyrin + 3 H 2 O + 2 NADP + (overall reaction)
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Oxofluoxymesterone (developmental code name U-6596), or ketofluoxymesterone, is an androgen and anabolic steroid (AAS) which was never marketed. [1] [2] [3] It was assessed in the treatment of breast cancer in women in the 1970s and showed effectiveness similar to that of other AAS.