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Because brand name Viagra, also known as sildenafil citrate, is thought of as a “cure-all” for intimate ailments (but mostly for ED), many men turn to it as a solution to the oldest problem ...
Last but not least, using Viagra when you don’t have ED brings the risk of poisoning. Some of the pills out there could be counterfeits or may be manufactured in unsafe environments.
After further trials, sildenafil citrate was approved by the Food and Drug Administration (FDA) in 1998 as the active ingredient in brand name Viagra, now a very well-known drug for ED.
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
Figure 3. A flow chart showing the relationship between different parts (domains) of PDE5-inhibitors. Figure 4. A representation of the 3D structure of sildenafil, a common PDE5-inhibitor. The PDE5 inhibitors sildenafil, vardenafil and tadalafil are competitive and reversible inhibitors of cGMP hydrolysis by the catalytic side of PDE5.
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