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Increasing age, with the highest risk after ages 45 in men and 55 in women Being assigned male at birth Family history, especially having a genetic disorder called familial hypercholesterolemia
There is evidence from systematic review and meta-analyses that statins, particularly atorvastatin, reduce both decline in kidney function (eGFR) and the severity of protein excretion in urine, [28] [29] [30] with higher doses having greater effect. [29] [30] Data are conflicting for whether statins reduce risk of kidney failure. [28]
The recommendations for cholesterol management through lifestyle changes from the National Cholesterol Education Program have evolved over time based on data from epidemiological observations, animal studies, and clinical trials. Animal models have demonstrated a direct relationship between LDL cholesterol and atherosclerosis. Animals consuming ...
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
In fact, sticking close to the diet has recently been shown, in a large-scale, long-term (30-year) cohort study published last year in the journal Circulation, to lower heart disease risk by 14%.
In people over the age of 70, statins decrease the risk of cardiovascular disease but only in those with a history of heavy cholesterol blockage in their arteries. [ 24 ] Most evidence suggests that statins are also effective in preventing heart disease in those with high cholesterol but no history of heart disease.
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Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood).
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