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Acetylcholine binds to nicotinic acetylcholine receptors of alpha-motor neurons. [3] The somatic nervous system controls all voluntary muscular systems within the body, and the process of voluntary reflex arcs. [10] The basic route of nerve signals within the efferent somatic nervous system involves a sequence that begins in the upper cell ...
The general (spinal) somatic efferent neurons (GSE, somatomotor, or somatic motor fibers) arise from motor neuron cell bodies in the ventral horns of the gray matter within the spinal cord. They exit the spinal cord through the ventral roots , carrying motor impulses to skeletal muscle through a neuromuscular junction .
A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
Upper motor neurons (UMNs) is a term introduced by William Gowers in 1886. They are found in the cerebral cortex and brainstem and carry information down to activate interneurons and lower motor neurons, which in turn directly signal muscles to contract or relax. UMNs represent the major origin point for voluntary somatic movement.
The opposite direction of neural activity is afferent conduction, [2] [3] [4] which carries impulses by way of the afferent nerve fibers of sensory neurons. In the nervous system, there is a "closed loop" system of sensation, decision, and reactions. This process is carried out through the activity of sensory neurons, interneurons, and motor ...
In case of neurons, the soma receives a large number of inhibitory synapses, [6] which can regulate the activity of these cells. It has also been shown that microglial processes constantly monitor neuronal functions through somatic junctions, and exert neuroprotection when needed.
The central nervous system is responsible for the orderly recruitment of motor neurons, beginning with the smallest motor units. [4] Henneman's size principle indicates that motor units are recruited from smallest to largest based on the size of the load. For smaller loads requiring less force, slow twitch, low-force, fatigue-resistant muscle ...
Once the neurons have reached their regional positions, they extend axons and dendrites, which allow them to communicate with other neurons via synapses. Synaptic communication between neurons leads to the establishment of functional neural circuits that mediate sensory and motor processing, and underlie behavior. [12]