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Antipsychotic abuse refers to the non-medical or inappropriate use of antipsychotic medications for purposes other than their intended therapeutic use. Antipsychotics, also known as neuroleptics, are a class of medications primarily used in treating psychiatric disorders such as schizophrenia , bipolar disorder , and certain types of depression .
Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [ 14 ] and as an appetite stimulant . [ 15 ]
Very common adverse effects of olanzapine, occurring more than 10%, include: Weight gain (dose-dependent). Weight gain of over 7% of a person's initial body weight prior to treatment is in this category of very common too with some estimates of its incidence putting it at around 40.6%.
They may cause irritability and withdrawal and, in some cases, lead to psychosis that requires hospitalization. ... Illicit drug use and substance abuse. ... Olanzapine (Zyprexa®) Cariprazine ...
Olanzapine, another sedating second-generation antipsychotic, has also been misused for similar reasons. [292] There is no standard treatment for antipsychotic abuse, though switching to a second-generation antipsychotic with less abuse potential (e.g., aripiprazole) has been used. [292]
In the U.S., Zyprexa (olanzapine) is approved by the FDA for the treatment of schizophrenia and bipolar disorder. In 2010 , Zyprexa's worldwide revenues were just over $5 billion, or nearly 22% of ...
In January, 2020, Gottstein published a book titled The Zyprexa Papers giving his first-hand account of how he obtained the Zyprexa papers, including how Will Hall and a small group of psychiatric survivors untraceably spread the Zyprexa Papers on the Internet and his battles on behalf of Bill Bigley, the psychiatric patient whose ordeal made ...
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...