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Most Pax genes contain a homeobox and a paired domain that also binds DNA to increase binding specificity, though some Pax genes have lost all or part of the homeobox sequence. [46] Pax genes function in embryo segmentation , nervous system development, generation of the frontal eye fields , skeletal development, and formation of face structures.
3200 15400 Ensembl ENSG00000105997 ENSMUSG00000079560 UniProt O43365 P02831 RefSeq (mRNA) NM_030661 NM_153631 NM_153632 NM_010452 RefSeq (protein) NP_109377 NP_705895 NP_034582 Location (UCSC) Chr 7: 27.11 – 27.15 Mb Chr 6: 52.15 – 52.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene. Function In ...
Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene. [5] [6] [7] This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene ...
15434 Ensembl ENSG00000128652 ENSMUSG00000079277 UniProt P31249 P09027 RefSeq (mRNA) NM_006898 NM_010468 RefSeq (protein) NP_008829 NP_034598 Location (UCSC) Chr 2: 176.14 – 176.17 Mb Chr 2: 74.54 – 74.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-D3 is a protein that in humans is encoded by the HOXD3 gene. Function This gene belongs to the homeobox ...
209448 Ensembl ENSG00000180818 ENSMUSG00000022484 UniProt Q9NYD6 P31257 RefSeq (mRNA) NM_017409 NM_010462 RefSeq (protein) NP_059105 NP_034592 Location (UCSC) Chr 12: 53.99 – 53.99 Mb Chr 15: 102.88 – 102.88 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C10 is a protein that in humans is encoded by the HOXC10 gene. Function This gene belongs to the homeobox ...
LBX2 is a member of the ladybird family of homeobox genes, which are crucial in developmental processes. In rodent studies, LBX2 has been found to be expressed in various developing systems, notably the urogenital system, eye, and brain. [10] CRISPR/Cas9 technology has been used to create zebrafish models lacking LBX2. Observations of these ...
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The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters , HOXA, HOXB, HOXC and HOXD, located on different chromosomes , consisting of 9 to 11 genes arranged in tandem.