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Increased levels of these hormones will cause the body to not start puberty, not undergo menarche, and not develop secondary sex characteristics. [9] [10] If ovarian tissue is present and produces some amount of hormones, limited menstrual cycles can occur. [9] 46,XX gonadal dysgenesis can manifest from a variety of causes. [6]
Ovarian diseases refer to diseases or disorders of the ovary. [1] These can be classified as endocrine disorders or as a disorders of the reproductive system. If the egg fails to release from the follicle in the ovary an ovarian cyst may form. Small ovarian cysts are common in healthy women.
Female genital disease is a disorder of the structure or function of the female reproductive system that has a known cause and a distinctive group of symptoms, signs, or anatomical changes. The female reproductive system consists of the ovaries , fallopian tubes , uterus , vagina , and vulva .
(A female may carry such a disease on one X chromosome but not show symptoms if the other X chromosome works sufficiently.) For this reason, such conditions are far more common in males than in females. X-linked recessive disorders include: [129] Red-green colour blindness; Haemophilia A (factor VIII) Haemophilia B (factor IX) Duchenne Muscular ...
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
XX gonadal dysgenesis is a type of female hypogonadism in which the ovaries do not function to induce puberty in a person assigned female at birth, whose karyotype is 46,XX. [1] Individuals with XX gonadal dysgenesis have normal-appearing external genitalia as well as Müllerian structures (e.g., cervix, vagina, uterus).
Specific reproductive diseases are often symptoms of other diseases and disorders, or have multiple, or unknown causes making them difficult to classify. Examples of unclassifiable disorders are Peyronie's disease in males and endometriosis in females. Many congenital conditions cause reproductive abnormalities, but are better known for their ...
Fragile X-associated primary ovarian insufficiency (FXPOI) is the most common genetic cause of premature ovarian failure in women with a normal karyotype 46,XX. [1] The expansion of a CGG repeat in the 5' untranslated region of the FMR1 gene from the normal range of 5-45 repeats to the premutation range of 55-199 CGGs leads to risk of FXPOI for ovary-bearing individuals. [2]