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An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.
This molecule does not affect coagulation: 4-Hydroxycoumarin This molecule does not affect coagulation, but is a known carcinogen in diesel fumes and tobacco smoke; in the latter, it probably derives from combustion of the tobacco additive coumarin. Dicumarol This molecule was the first discovered 4-hydroxycoumarin anticoagulant.
Anticoagulants are considered more aggressive than antiplatelet drugs. [34] Anticoagulants work by interfering with various clotting factors to lengthen the time for coagulation. This can be achieved by either reducing the formation of bioactive clotting factors or accelerating the inactivation of clotting factors.
Warfarin, sold under the brand name Coumadin among others, is an anticoagulant medication. [12] While the drug is described as a "blood thinner", it does not reduce viscosity but rather prevents blood clots from forming (coagulating).
The use of LMWH has allowed once-daily dosing, thus not requiring a continuous infusion of the drug. If long-term anticoagulation is required, heparin is often used only to commence anticoagulation therapy until an oral anticoagulant e.g. warfarin takes effect. The American College of Chest Physicians publishes clinical guidelines on heparin ...
Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. People admitted to hospital requiring blood thinning were started on an infusion of heparin infusion, which thinned blood ...
The tube contains bromadiolone, a second-generation (superwarfarin) anticoagulant. The label in Dutch states, in part: Contains an anticoagulant with prolonged activity. Antidote Vitamin K1. Vitamin K 2 (menaquinone). In menaquinone the side chain is composed of a varying number of isoprenoid residues.
Pages in category "Anticoagulants" The following 31 pages are in this category, out of 31 total. This list may not reflect recent changes. * Anticoagulant;