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  2. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92]

  3. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Remeron (mirtazapine) – an atypical antidepressant, used off-label as a sleep aid; Restoril – a benzodiazepine used to treat insomnia; Risperdal (risperidone) – atypical antipsychotic used to treat schizophrenia, bipolar disorder and irritability associated with autism; Ritalin (methylphenidate) – a stimulant used to treat ADHD

  4. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]

  5. Tetracyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tetracyclic_antidepressant

    Besides mirtazapine, they also block the α 1-adrenergic receptor [citation needed]. Conversely, whereas TCAs have relatively low affinity for the α 2 -adrenergic receptor , mianserin and mirtazapine potently antagonize this receptor, and this action is thought to be involved in their antidepressant effects [ citation needed ] .

  6. Atypical antidepressant - Wikipedia

    en.wikipedia.org/wiki/Atypical_antidepressant

    An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Atypical antidepressants include agomelatine, bupropion, iprindole, mianserin, mirtazapine, nefazodone, opipramol, tianeptine, and trazodone.

  7. Here's why the Kroger merger with Albertsons was killed - AOL

    www.aol.com/heres-why-kroger-merger-albertsons...

    Kroger’s $25 billion proposed takeover of rival Albertsons ultimately failed because two judges – one federal and the other from the state of Washington – didn’t buy the competitive vision ...

  8. Alpha-2 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-2_blocker

    The tetracyclic antidepressants mianserin and mirtazapine are α 2 blockers, although their efficacy as antidepressants may come from their activity at other receptor sites. [citation needed] Mechanistically, α 2 blockers increase adrenergic, dopaminergic and serotonergic neurotransmitters and induce insulin secretion, decreasing blood sugar ...

  9. Mianserin - Wikipedia

    en.wikipedia.org/wiki/Mianserin

    Mirtazapine was developed by the same team of organic chemists and differs via addition of a nitrogen atom in one of the rings. [ 43 ] [ 44 ] ( S )-(+)-Mianserin is approximately 200–300 times more active than its enantiomer ( R )-(−)-mianserin; hence, the activity of mianserin lies in the ( S )-(+) isomer .

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