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A local anesthetic is a drug that causes reversible local anesthesia and a loss of nociception.When it is used on specific nerve pathways (nerve block), effects such as analgesia (loss of pain sensation) and paralysis (loss of muscle power) can be achieved.
New York State College of Human Ecology. (1984). Some ways to find out about child abuse and neglect, child welfare, adoption of children with special needs, troubled adolescents. Ithaca, N.Y: Family Life Development Center, Region II Resource Center on Children and Youth, Cornell University. [31] New York State College of Human Ecology. (1981).
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Anesthesiology, anaesthesiology or anaesthesia is the medical specialty concerned with the total perioperative care of patients before, during and after surgery. [1] It encompasses anesthesia, intensive care medicine, critical emergency medicine, and pain medicine. [2]
Sevoflurane, sold under the brand name Sevorane, among others, is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset. [8]
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MEGX has a longer half-life than lidocaine, but also is a less potent sodium channel blocker. [49] The volume of distribution is 1.1 L/kg to 2.1 L/kg, but congestive heart failure can decrease it. About 60% to 80% circulates bound to the protein alpha 1 acid glycoprotein .