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Vosoritide works by binding to a receptor (target) called natriuretic peptide receptor type B (NPR-B), which reduces the activity of fibroblast growth factor receptor 3 (FGFR3). [5] FGFR3 is a receptor that normally down-regulates cartilage and bone growth when activated by one of the proteins known as acidic and basic fibroblast growth factor.
Rindopepimut is the epidermal growth factor receptor (EGFR)-derived peptide vaccine to treat glioblastoma multiforme (GBM). The 14-mer peptide is coupled with keyhole limpet hemocyanin (KLH), which can reduce the risk of cancer. [11] E75, GP2, and AE37 are three different HER2/neu-derived single-peptide vaccines to treat breast cancer. HER2/neu ...
Semaglutide is a glucagon-like peptide-1 receptor agonist. It works by mimicking GLP-1 hormone, which is naturally produced in your intestines. ... There are a few injection sites you can use to ...
Peptide therapeutics are peptides or polypeptides (oligomers or short polymers of amino acids) which are used to for the treatment of diseases. Naturally occurring peptides may serve as hormones , growth factors , neurotransmitters , ion channel ligands , and anti-infectives ; peptide therapeutics mimic such functions.
The bioavailability of bremelanotide with subcutaneous injection is about 100%. [1] Following a subcutaneous injection of bremelanotide, maximal levels occur after about one hour, with a range of 0.5 to 1.0 hours. [1] The plasma protein binding of bremelanotide is 21%. [1] Bremelanotide is metabolized via hydrolysis of its peptide bonds. [1]
Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical ...
Liraglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also known as incretin mimetics. [6] It works by increasing insulin release from the pancreas and decreases excessive glucagon release. [6] Common side effects include low blood sugar, nausea, dizziness, abdominal pain, and pain at the site of injection.
[11] [16] Tirzepatide is administered via subcutaneous injections (under the skin). [10] [13] It is sold under the brand name Mounjaro for diabetes treatment, [10] and Zepbound for weight loss and treatment of obstructive sleep apnea. [11] [17] Tirzepatide is a gastric inhibitory polypeptide analog and GLP-1 receptor agonist. [11]