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Carboplatin, sold under the brand name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer. [3] This includes ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma. [3] It is used by injection into a vein. [3] Side effects generally occur. [3]
Carboplatin Carboplatin, like cisplatin, is composed of a central atom of platinum and two ammonia molecules, but it has a cyclobutanedicarboxylate moiety instead of chloride. Carboplatin is also provided intravenously and also kills cells by disrupting the cell's DNA. Bone marrow suppression is the dose-limiting toxicity of carboplatin.
In the European Union, dostarlimab is indicated as monotherapy for the treatment of adults with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI H) recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-based regimen such as cisplatin, carboplatin or oxaliplatin. [15]
They are given by injection. [2] Common side effects may include joint pain, rash, vomiting, and headache. [4] Serious side effects may include heart attacks, stroke, increased cancer growth, or pure red cell aplasia. [2] It is unclear if use is safe during pregnancy. [5] [6] They work similar to naturally occurring erythropoietin. [1]
Side effects of thalidomide-induced peripheral neuropathy include sensory symptoms, possible motor impairment, and gastrointestinal and cardiovascular autonomic manifestations. The symptoms of immunomodulatory drugs may dictate whether treatment is continued or discontinued, and they can last long-term after chemotherapy completion.
Cosmetic injectables are on the rise and with them, telltale side effects like swelling, redness, and bruising. But the right post-injection skincare can help.
The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.
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