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An odds ratio (OR) is a statistic that quantifies the strength of the association between two events, A and B. The odds ratio is defined as the ratio of the odds of event A taking place in the presence of B, and the odds of A in the absence of B. Due to symmetry, odds ratio reciprocally calculates the ratio of the odds of B occurring in the presence of A, and the odds of B in the absence of A.
In medical testing with binary classification, the diagnostic odds ratio (DOR) is a measure of the effectiveness of a diagnostic test. [1] It is defined as the ratio of the odds of the test being positive if the subject has a disease relative to the odds of the test being positive if the subject does not have the disease.
Tests for interaction for the risk ratio, odds ratio, and risk difference; Four different confidence limit methods for the odds ratio. Similar to Epi Info, in a stratified analysis, both crude and adjusted estimates are provided so that the assessment of confounding can be made.
In practice the odds ratio is commonly used for case-control studies, as the relative risk cannot be estimated. [1] In fact, the odds ratio has much more common use in statistics, since logistic regression, often associated with clinical trials, works with the log of the odds ratio, not relative risk. Because the (natural log of the) odds of a ...
and = / / = While the prevalence is only 9% (9/100), the odds ratio (OR) is equal to 11.3 and the relative risk (RR) is equal to 7.2. Despite fulfilling the rare disease assumption overall, the OR and RR can hardly be considered to be approximately the same. However, the prevalence in the exposed group is 40%, which means is not sufficiently small
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health , and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare .
The simplest measure of association for a 2 × 2 contingency table is the odds ratio. Given two events, A and B, the odds ratio is defined as the ratio of the odds of A in the presence of B and the odds of A in the absence of B, or equivalently (due to symmetry), the ratio of the odds of B in the presence of A and the odds of B in the absence of A.
Although in classical case–control studies, it remains true that the odds ratio can only approximate the relative risk in the case of rare diseases, there is a number of other types of studies (case–cohort, nested case–control, cohort studies) in which it was later shown that the odds ratio of exposure can be used to estimate the relative ...