Search results
Results from the WOW.Com Content Network
The college's origins date back to the seventeenth century. In 1695, a Congregation Fund was created in London to educate Calvinist ministers. As non-conformists, they were barred by law from attending Oxbridge colleges, and so studied a modern curriculum, with particular emphasis on philosophy, science, and modern history. [6]
The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. [5] [6] It is closely related to the cannabinoid receptor 1 (CB1), which is largely responsible for the efficacy of endocannabinoid-mediated presynaptic-inhibition, the psychoactive properties of tetrahydrocannabinol (THC), the active agent in ...
A neurotransmitter for a possible endocannabinoid system in the brain and peripheral nervous system, anandamide (from 'ananda', Sanskrit for 'bliss'), was first characterized in 1992, [18] [19] [20] followed by discovery of other fatty acid neurotransmitters that behave as endogenous cannabinoids having a low-to-high range of efficacy for ...
GW-405,833 (L-768,242) is a drug that acts as a potent and selective partial agonist for the cannabinoid receptor subtype CB 2, with an EC 50 of 0.65 nM and selectivity of around 1200x for CB 2 over CB 1 receptors.
CB2 or similar, may refer to: Cannabinoid receptor type 2; Crash Bandicoot 2: Cortex Strikes Back, a video game developed by Naughty Dog for PlayStation; CB2, a division of Crate & Barrel; Child-robot with Biomimetic Body - a Robot at the Osaka University that mimics infant learning. USS Guam
The endogenous cannabinoid system includes cannabinoid receptors, their endogenous ligands (endocannabinoids) and enzymes for their synthesis and degradation. [13]There are two main receptor types associated with the endocannabinoid signaling system: cannabinoid receptor 1 (CB 1) and 2 (CB 2).
Cannabinol (CBN) is a mildly psychoactive phytocannabinoid that acts as a low affinity partial agonist at both CB 1 and CB 2 receptors.This activity at CB 1 and CB 2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS).
2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB 1 receptor and the primary endogenous ligand for the CB2 receptor. [1] [2] It is an ester formed from the omega-6 fatty acid arachidonic acid and glycerol. It is present at relatively high levels in the central nervous system, with cannabinoid neuromodulatory ...