Search results
Results from the WOW.Com Content Network
Pergolide acts as an agonist of dopamine D 2 and D 1 and serotonin 5-HT 1A, 5-HT 1B, 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors.It may possess agonist activity at other dopamine receptor subtypes as well, similar to cabergoline.
15550 Ensembl ENSG00000178394 ENSMUSG00000021721 UniProt P08908 Q64264 RefSeq (mRNA) NM_000524 NM_008308 RefSeq (protein) NP_000515 NP_032334 Location (UCSC) Chr 5: 63.96 – 63.96 Mb Chr 13: 105.58 – 105.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serotonin 1A receptor (or 5-HT 1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin ...
The 5-HT 1 subfamily consists of five G protein-coupled receptors (GPCRs) that share 40% to 63% overall sequence homology, including 5-HT 1A, 5-HT 1B, 5-HT 1D, 5-HT 1E, and 5-HT 1F. [2] Receptors of the 5-HT 1 type, specifically, the 5-HT 1A and 5-HT 1D receptor subtypes, are present on the cell bodies. Receptors of the 5-HT1 type, specifically ...
TGBA01AD (also known as FKB01MD) is a serotonin reuptake inhibitor, 5-HT 1A and 5-HT 1D receptor agonist, and 5-HT 2 receptor antagonist which is under development by Fabre-Kramer for the treatment of major depressive disorder. [2] [1] [3] It has been in phase II clinical trials since 2009, and as of January 2016, remains in this phase of ...
F-15,599, also known as NLX-101, is a potent and selective 5-HT 1A receptor full agonist. [1] [2] In addition, it displays functional selectivity, or biased agonism, by preferentially activating postsynaptic serotonin 5-HT 1A receptors over somatodendritic serotonin 5-HT 1A autoreceptors.
3351 15551 Ensembl ENSG00000135312 ENSMUSG00000049511 UniProt P28222 P28334 RefSeq (mRNA) NM_000863 NM_010482 RefSeq (protein) NP_000854 NP_034612 Location (UCSC) Chr 6: 77.46 – 77.46 Mb Chr 9: 81.51 – 81.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 5-hydroxytryptamine receptor 1B also known as the 5-HT 1B receptor is a protein that in humans is encoded by the HTR1B gene ...
The drug produces MDMA-like locomotor hyperactivity in animals and this is thought to be mediated by activation of both serotonin 5-HT 1A and 5-HT 1B receptors. [4] [1] [5] [6] [7] As with other serotonin 5-HT 1B receptor agonists such as CP-94,253, RU-24,969 has also been found to increase the reinforcing properties of cocaine in animals ...
5-Hydroxytryptamine (serotonin) receptor 5A, also known as HTR5A, is a protein that in humans is encoded by the HTR5A gene. [5] [6] Agonists and antagonists for 5-HT receptors, as well as serotonin uptake inhibitors, present promnesic (memory-promoting) and/or anti-amnesic effects under different conditions, and 5-HT receptors are also associated with neural changes.