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  2. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  3. CRISPR RNA - Wikipedia

    en.wikipedia.org/wiki/CRISPR_RNA

    CRISPR RNA or crRNA is a RNA transcript from the CRISPR locus. [1] CRISPR-Cas (clustered, regularly interspaced short palindromic repeats - CRISPR associated systems) is an adaptive immune system found in bacteria and archaea to protect against mobile genetic elements , like viruses , plasmids , and transposons . [ 2 ]

  4. File:The Stages of CRISPR immunity.svg - Wikipedia

    en.wikipedia.org/wiki/File:The_Stages_of_CRISPR...

    English: The stages of CRISPR immunity for each of the three major divisions. (1) Acquisition begins by recognition of invading DNA by Cas1 and Cas2 and cleavage of a protospacer. (2) The protospacer is ligated to the direct repeat adjacent to the leader sequence and (3) single strand extension repairs the CRISPR and duplicates the direct repeat.

  5. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR-Cas9. CRISPR gene editing (CRISPR, pronounced / ˈ k r ɪ s p ə r / (crisper), refers to a clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified.

  6. Cas9 - Wikipedia

    en.wikipedia.org/wiki/Cas9

    More technically, Cas9 is a RNA-guided DNA endonuclease enzyme associated with the Clustered Regularly Interspaced Short Palindromic Repeats adaptive immune system in Streptococcus pyogenes. [3] [4] [5] S. pyogenes utilizes CRISPR to memorize and Cas9 to later interrogate and cleave foreign DNA, such as invading bacteriophage DNA or plasmid DNA.

  7. Cas12a - Wikipedia

    en.wikipedia.org/wiki/Cas12a

    The CRISPR-Cas12a system consist of a Cas12a enzyme and a guide RNA that finds and positions the complex at the correct spot on the double helix to cleave target DNA. CRISPR-Cas12a systems activity has three stages: [3] Adaptation: Cas1 and Cas2 proteins facilitate the adaptation of small fragments of DNA into the CRISPR array.

  8. Valerie Bertinelli Shares Bikini Mirror Selfie and Hints at ...

    www.aol.com/lifestyle/valerie-bertinelli-shares...

    Valerie Bertinelli is embracing her body.. The Food Network alum, 64, posted a mirror selfie on Instagram while opening up about the acceptance she felt for her body despite the tough things it ...

  9. Anti-CRISPR - Wikipedia

    en.wikipedia.org/wiki/Anti-CRISPR

    Phage therapy is a good alternative to the use of antibiotics, but some bacteria have CRISPR-Cas systems. Nevertheless, if phages had Acr proteins, they would inhibit the CRISPR-Cas immune system and infect the cell. At the end of the phage reproduction cycle, which takes place inside bacteria, new phages would be released, provoking the cell ...

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