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Multi-infarct dementia results from a series of small strokes affecting several brain regions. Stroke-related dementia involving successive small strokes causes a more gradual decline in cognition. [4] Dementia may occur when neurodegenerative and cerebrovascular pathologies are mixed, as in susceptible elderly people (75 years and older).
Binswanger's disease, also known as subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy, [1] is a form of small-vessel vascular dementia caused by damage to the white brain matter. [2] White matter atrophy can be caused by many circumstances including chronic hypertension as well as old age. [3]
It is one of the most common causes of disability among the elderly but can develop before the age of 65 when it is known as early-onset dementia or presenile dementia. [ 283 ] [ 284 ] Less than 1% of those with Alzheimer's have gene mutations that cause a much earlier development of the disease, around the age of 45, known as early-onset ...
Recent research is looking at the way in which cardiovascular issue may play into the development of dementia, with one ... cell surface molecules ... strokes caused [by] multi-infarct dementia ...
A person can show one or more of these symptoms during a stroke. Decreased consciousness is more uncommon than in stroke due to intracerebral hemorrhage, but may be present when there is infarctions in more than one part of the brain or in the brain stem. [13] Symptoms of cerebral infarction can help determine which parts of the brain are affected.
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
Microinfarcts may be the second most important cause of dementia, after Alzheimer's disease. [3] [4] Microinfarcts are microscopic lesions, of cellular death or tissue necrosis, which are a result of pathologies involving small vessels. Such pathologies are arteriosclerosis or cerebral amyloid angiopathy. [5]
That’s because dementia first affects the part of the brain that’s responsible for short-term memories, as opposed to long-term memories, said Newhouse.
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