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As a result, this type of biologic inhibits T cell proliferation and B cell immunological response. [20] Abatacept is available as an antiarthritic medication for moderate to severe RA. This biologic can also be used to treat patients with juvenile rheumatoid arthritis. [14] Examples: [16] Abatacept
Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.
rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn's disease, ulcerative colitis Intetumumab [83] [84] mab: human: CD51: solid tumors (prostate cancer, melanoma) Inolimomab: mab: mouse: CD25 (α chain of IL-2 receptor) graft versus host disease Inotuzumab ozogamicin [39] Besponsa: mab: humanized: CD22: Y: Acute ...
For people with moderate to severe psoriatic arthritis, biologics can provide some relief of the symptoms, [4] and even slow down or halt the progression of the disease. Classes of biologics typically used for psoriatic arthritis include TNF inhibitors, anti-IL17-A antibodies, IL-23 antibodies, and those that act on both IL-12 and IL-23. [7]
Although the use of the term DMARDs was first propagated in rheumatoid arthritis (hence their name), the term has come to pertain to many other diseases, such as Crohn's disease, lupus erythematosus, Sjögren syndrome, immune thrombocytopenic purpura, myasthenia gravis, sarcoidosis, and various others. [citation needed]
It was approved for treating ankylosing spondylitis, [33] psoriatic arthritis, psoriasis, rheumatoid arthritis. [34] Infliximab is also prescribed (out of indication) for the treatment of Behçet's disease. [35] Infliximab is the most frequently used biological agent in treating relapsing polychondritis. [36]
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