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Estrogen also rises during pregnancy, and that, combined with progesterone, can contribute to the formation of melasma, which appears as dark brown spots or patches.
Examples of such side effects include breast tenderness and enlargement, nausea, bloating, edema, headache, and melasma. [15] [62] High-dose estrogen therapy with estradiol valerate injections may also cause an increased risk of thromboembolism, changes in blood lipid profile, increased insulin resistance, and increased levels of prolactin. [62]
Examples of such side effects include breast tenderness and enlargement, nausea, vomiting, bloating, edema, headache, migraine, and melasma. [54] [55] High-dose estrogen therapy with estradiol cypionate injections may also cause an increased risk of thromboembolism, changes in blood lipid profile, increased insulin resistance, and increased ...
What causes melasma? In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles , MO, a family physician ...
List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
What is melasma? “Melasma is a skin condition marked by a darkening of the skin, specifically of the face,” says Amy Wechsler, MD, FAAD, a New York City-based, double board-certified ...
The symptoms of melasma are dark, irregular, well-demarcated, hyperpigmented macules to patches. These patches often develop gradually over time. Melasma does not cause any other symptoms beyond the cosmetic discoloration. [4] Patches can vary in size from 0.5 cm (0.2 in) to larger than 10 cm (4 in) depending on the person.
“Even with the best treatments, melasma may not completely resolve,” Dr. Rodney says. “The good news is that there are options to help reduce the appearance of the discoloration.”
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