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You can take semaglutide for weight loss indefinitely. There’s no set cut-off time, as the drug was originally designed as a diabetes medication and intended for long-term use.
Semaglutide works best for weight loss for people who use it in addition to lifestyle and diet modifications, says Dr. Kumar. This includes exercising (which can also help maintain muscle mass ...
Some injectables are FDA-approved for weight loss, and others are used off-label for weight loss. FDA-approved weight loss drugs include Wegovy (semaglutide), Saxenda (liraglutide), and Zepbound ...
Both are more effective than any previous weight loss drugs. Studies show that people taking semaglutide can lose around 15% of their body weight, and people taking tirzepatide can lose more than 20%.
Preliminary trial results found a greater weight loss compared to either medication alone. HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. [1] [2] In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide.
In March 2023, a Novo Nordisk official said, based on a randomized, double-blind study (NCT03548935 [112]) funded by the company, that patients using semaglutide to lose weight regained two-thirds of their original weight loss one year (52 weeks) after discontinuing use of the drug. After two years (120 weeks), the patients retained roughly one ...
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