Ads
related to: linezolid action
Search results
Results from the WOW.Com Content Network
Linezolid binds to the 23S portion of the 50S subunit (the center of peptidyl transferase activity), [9] [101] close to the binding sites of chloramphenicol, lincomycin, and other antibiotics. Due to this unique mechanism of action, cross-resistance between linezolid and other protein synthesis inhibitors is highly infrequent or nonexistent ...
Mechanism of action: Enzyme inhibitor: Biological target: Monoamine oxidase enzymes: ... Linezolid is an antibiotic drug with weak, reversible MAO-inhibiting activity.
Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Nitrofurans; Furazolidone: Furoxone: Bacterial or protozoal diarrhea or enteritis: Nitrofurantoin(Bs) Macrodantin, Macrobid: Urinary tract infections: Oxazolidinones(Bs) Linezolid: Zyvox: VRSA: Thrombocytopenia ...
Linezolid (Zyvox), which is available for intravenous administration and also has the advantage of having excellent oral bioavailability. Posizolid , which appears to have excellent, targeted bactericidal activity against all common gram-positive bacteria, regardless of resistance to other classes of antibiotics.
Lincosamides consist of a pyrrolidine ring linked to a pyranose moiety (methylthio-lincosamide) via an amide bond. [2] [3] Hydrolysis of lincosamides, specifically lincomycin, splits the molecule into its building blocks of the sugar and proline moieties.
The search engine that helps you find exactly what you're looking for. Find the most relevant information, video, images, and answers from all across the Web.
Rivaroxaban bears a striking structural similarity to the antibiotic linezolid: both drugs share the same oxazolidinone-derived core structure. [39] Accordingly, rivaroxaban was studied for any possible antimicrobial effects and for the possibility of mitochondrial toxicity, which is a known complication of long-term linezolid use. [40]
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Ads
related to: linezolid action