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A bioinformatics network analysis is one approach to this problem. Network analyses methodologies provide a generalized, systems overview of a molecular pathway. One final complication to consider is the comorbidity of neurogenomic genes. Several disorders, especially at the more severe ends of the spectrum tend to be comorbid with each other.
The specific type of LTP exhibited between neurons depends on a number of factors. One such factor is the age of the organism when LTP is observed. For example, the molecular mechanisms of LTP in the immature hippocampus differ from those mechanisms that underlie LTP of the adult hippocampus. [22]
Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...
Molecular Neurobiology is a bimonthly peer-reviewed scientific journal covering all aspects of molecular ... the journal has a 2020 impact factor of 5.590. [1] References
Molecular neuroscience is a branch of neuroscience that examines the biology of the nervous system with molecular biology, molecular genetics, protein chemistry and related methodologies (ie. concerning neurotransmitters moving via physiology of synapses etc) Neurochemistry; Nutritional neuroscience; Neuropeptide [ also see Neuropharmacology above]
One such protein pathway is the REST co-repressor complex pathway. There are also several non-coding RNAs that regulate neural function at the epigenetic level. These mechanisms, along with neural histone methylation , affect arrangement of synapses , neuroplasticity, and play a key role in learning and memory.
One of the most noticeable results of further research into neurogenetics is a greater knowledge of gene loci that show linkage to neurological diseases. The table below represents a sampling of specific gene locations identified to play a role in selected neurological diseases based on prevalence in the United States. [9] [10] [11] [12]
He was also one of the first scientists to believe that through chemical means, the vast majority of neurological diseases could be treated, if not cured. [ 2 ] Irvine Page (1901-1991) was an American psychologist that published the first major textbook focusing on neurochemistry in 1937.