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Most importantly, zimelidine did not come with the adverse effect profile as the TCAs and therefore it became the template for the second generation SSRIs. [6] Zimelidine was the first SSRI to be marketed, but several cases of Guillain–Barré syndrome were associated with the use of the drug which led to withdrawal from the market in 1983.
Template: Antidepressants. ... View history; General What links here; ... Page information; Get shortened URL; Download QR code; Print/export Download as PDF ...
1808. German physician Johann Christian Reil coined the term "psychiatry". [9]1812. American physician Benjamin Rush became one of the earliest advocates of humane treatment for the mentally ill with the publication of Medical Inquiries and Observations, upon the Diseases of the Mind, [10] the first American textbook on psychiatry.
The history of antidepressants. Most antidepressants aim for the same target: the monoamine system. They work by raising levels of one or more of the monoamine neurotransmitters in the brain that ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Critics of antidepressants maintain that the superiority of antidepressants over placebo is the result of systemic flaws in clinical trials and the research literature. [ 95 ] [ 87 ] Trials conducted with industry involvement tend to produce more favorable results, and accordingly many of the trials included in meta-analyses are at high risk of ...
It should only contain pages that are antidepressants or lists of antidepressants, as well as subcategories containing those things (themselves set categories). Topics about antidepressants in general should be placed in relevant topic categories .
The pharmacology of antidepressants is not entirely clear.. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). [1]