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Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. [9] Haloperidol is used in the treatment of schizophrenia , tics in Tourette syndrome , mania in bipolar disorder , delirium , agitation, acute psychosis , and hallucinations from alcohol withdrawal .
Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [ 6 ] [ 7 ] [ 9 ] Its elimination half-life after multiple doses is 21 days.
Pharmacokinetics of long-acting injectable antipsychotics; Medication Brand name Class Vehicle Dosage T max t 1/2 single t 1/2 multiple logP c Ref Aripiprazole lauroxil: Aristada: Atypical: Water a
If a scheduled injection of either haloperidol decanoate or fluphenazine decanoate is missed, recommendations for administering make-up injectable dose(s) or providing antipsychotics to be taken by mouth vary by, e.g., how long ago the last injection was and how many previous injections the person has received (i.e., if steady state levels of ...
Haloperidol decanoate, an antipsychotic ester. An antipsychotic ester is an ester of an antipsychotic . [ 1 ] They are used clinically as prodrugs to increase fat solubility and thereby prolong duration when antipsychotics are used as depot injectables .
Haldol had been invented in the laboratories of Paul Janssen, a legendary Belgium chemist whose father had founded a small pharmaceutical research lab in the 1930s. R.W. Johnson II had purchased the company in 1961 in what became a critical pivot by Johnson & Johnson away from medical supplies and toward the blossoming, high-margin prescription ...
Print/export Download as PDF; ... Dosage T max t 1/2 single t 1/2 multiple logP c Ref ... Haloperidol decanoate: Haldol Decanoate: Typical: Sesame oil:
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
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