Search results
Results from the WOW.Com Content Network
You are free: to share – to copy, distribute and transmit the work; to remix – to adapt the work; Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made.
NS1 antigen test (nonstructural protein 1) is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. [1] It has been adopted for use in some 40 nations. The method of detection is through enzyme-linked immunosorbent assay.
As a result, blood volume decreases, and the blood pressure becomes so low that it cannot supply sufficient blood to vital organs. The spread of the virus to the bone marrow leads to reduced numbers of platelets, which are necessary for effective blood clotting; this increases the risk of bleeding, the other major complication of dengue fever.
The test was once part of the World Health Organization (WHO) algorithm for diagnosis of dengue fever, [3] however it is no longer used in the latest WHO guidance. [4] Studies have shown that the tourniquet test has low predictive value for dengue fever and should be used in conjunction with other tests for a reliable diagnosis. [5] [6] [7] [8]
There are ELISA tests to detect various kind of diseases, such as dengue, malaria, Chagas disease, [30] Johne's disease, and others. [31] ELISA tests also are extensively employed for in vitro diagnostics in medical laboratories. The other uses of ELISA include: detection of SARS-CoV-2 antibodies in blood samples [32]
The tourniquet test, which is particularly useful in settings where no laboratory investigations are readily available, involves the application of a blood pressure cuff at between the diastolic and systolic pressure for five minutes, followed by the counting of any petechial hemorrhages; a higher number makes a diagnosis of dengue more likely.
The Hess test or Rumpel-Leede test is a medical test used to assess capillary fragility. [1] It is also called the Tourniquet test . To perform the test, pressure is applied to the forearm with a blood pressure cuff inflated to between systolic and diastolic blood pressure for 10 minutes.
Laboratory blood tests can identify evidence of chikungunya or other similar viruses such as dengue and Zika. [30] Blood test may confirm the presence of IgM and IgG anti-chikungunya antibodies. IgM antibodies are highest 3 to 5 weeks after the beginning of symptoms and will continue be present for about 2 months. [30]