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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
The fact that environmental exposures are heritable means that the relationship between environmental exposure and disease may be confounded by genotype. That is, the relationship may be spurious (not causal), because the same genetic factors might be influencing both exposure to environmental risk and disease. In such cases, measures aimed at ...
In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, [1] which may eventually be triggered by particular environmental or lifestyle factors, such as tobacco smoking or diet. Genetic testing is able to identify individuals who are genetically predisposed to certain diseases.
Scientists have found that people missing a specific blood group due to a genetic variant may be genetically predisposed to having obesity or ... 21 genes related to Alzheimer’s disease to obesity.
In this study, however, we found a clear genetic trigger for obesity,” said lead study author Dr. Mattia Frontini, British Heart Foundation senior fellow and an associate professor in cellular ...
The modern disease theory of alcoholism states that problem drinking is sometimes caused by a disease of the brain, characterized by altered brain structure and function. Today, alcohol use disorder (AUD) is used as a more scientific and suitable approach to alcohol dependence and alcohol-related problems. [1]
The main problem with this idea is the timing at which the transition is presumed to have happened, and how this would then translate into the genetic predisposition to type 2 diabetes and obesity [citation needed]. For example, the decline in reproductive investment in human societies (the so-called r to K shift) has occurred far too recently ...
Chronic alcohol exposure can itself cause epigenetic modifications, altering the expression of genes involved in alcohol metabolism, including ALDH2. [ 23 ] [ 25 ] Research shows that repeated alcohol intake can change DNA methylation across various genes, contributing to progressive alcohol sensitivity and amplifying the effects of genetic ...