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Lutein (/ ˈ lj uː t i ɪ n,-t iː n /; [2] from Latin luteus meaning "yellow") is a xanthophyll and one of 600 known naturally occurring carotenoids.Lutein is synthesized only by plants, and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots.
Zeaxanthin is one of the most common carotenoids in nature, and is used in the xanthophyll cycle.Synthesized in plants and some micro-organisms, it is the pigment that gives paprika (made from bell peppers), corn, saffron, goji (wolfberries), and many other plants and microbes their characteristic color.
A 2017 randomized controlled trial evaluated macular carotenoid supplements (lutein, zeaxanthin, and mesozeaxanthin) in people with high screen time usage. The supplement group had statistically significant reduction in self-reported headache, eye strain, eye fatigue and sleep complaints, but no reduction in neck strain or blurry vision. [9]
Berberine supplements, on the other hand, activate AMPK enzymes in your body, which work to regulate metabolism (offering potential benefits for weight loss), says Lee.
Lutein and zeaxanthin act as antioxidants that protect the retina and macula from oxidative damage from high-energy light waves. [106] As the light waves enter the eye, they excite electrons that can cause harm to the cells in the eye, but they can cause oxidative damage that may lead to macular degeneration or cataracts.
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