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Spasmolytics, also known as "centrally acting" muscle relaxant, are used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions. While both neuromuscular blockers and spasmolytics are often grouped together as muscle relaxant, [1] [2] the term is commonly used to refer to spasmolytics only ...
ATC code M03 Muscle relaxants is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup M03 is part of the anatomical group M Musculo-skeletal system. [4]
ATC code M Musculo-skeletal system is a section of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] [4]
Cyclobenzaprine is a centrally acting muscle relaxant with a chemical structure that is very similar to those of tricyclic antidepressants like amitriptyline and imipramine. [ 29 ] [ 6 ]
This category reflects the organization of Anatomical Therapeutic Chemical Classification System code M03. Generally, drugs outlined within the ATC code M03 should be included in this category. Please see WP:PHARM:CAT for more information.
Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It can also be administered for acute pain in general and for tension headache (muscle contraction headache). It acts on the spinal cord by depressing reflexes.
This causes prolonged stimulation and desensitization of neuroreceptors, causing skeletal muscle relaxation effects such as paralysis. [1] Depolarizing neuromuscular blockers, notably succinylcholine, tend to be preferred over non-depolarizing neuromuscular blockers due to their long-acting and rapid-onset properties. [1]
[3] [4] Because of the risk of injury, skeletal muscle relaxants should generally be avoided in geriatric patients. [3] Methocarbamol is a centrally acting muscle relaxant. [3] How it works is unclear, but it does not appear to affect muscles directly. [3] Methocarbamol was developed in 1956 in the laboratories of A. H. Robins (later acquired ...