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  2. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. [1] It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of cocaine and/or crack despite substantial harm and adverse consequences.

  3. Crack cocaine - Wikipedia

    en.wikipedia.org/wiki/Crack_cocaine

    Crack users tend to smoke the drug because that has a higher bioavailability than other routes typically used for drugs of abuse, such as insufflation. Crack has a melting point of around 90 °C (194 °F), [1] and the smoke does not remain potent for long. Therefore, crack pipes are generally very short, to minimize the time between evaporating ...

  4. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    A woman smoking crack cocaine "Rocks" of crack cocaine. Crack is usually smoked in a glass pipe, and once inhaled, it passes from the lungs directly to the central nervous system, producing an almost immediate "high" that can be very powerful – this initial crescendo of stimulation is known as a "rush". This is followed by an equally intense ...

  5. Nicotine dependence - Wikipedia

    en.wikipedia.org/wiki/Nicotine_dependence

    A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]

  6. Tobacco and other drugs - Wikipedia

    en.wikipedia.org/wiki/Tobacco_and_other_drugs

    Smoking may have a genetic predisposing factor; one 1990 study posited that 52% of the variance in smoking behaviour is attributable to heritable factors. [ 6 ] [ 7 ] The concept received support from a large-scale genetic analysis of 2016 that showed a genetic basis for the connection of the prevalence of cigarette smoking and cannabis use ...

  7. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  8. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  9. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    These costs arise from the direct adverse effects of drugs and associated healthcare costs (e.g., emergency medical services and outpatient and inpatient care), long-term complications (e.g., lung cancer from smoking tobacco products, liver cirrhosis and dementia from chronic alcohol consumption, and meth mouth from methamphetamine use), the ...