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Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5 × 10 8 /L (500/μL). [1] Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 10 9 / L (i.e. 1,500/ μL ).
Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.
Laboratory tests typical of chronic eosinophilic pneumonia include increased levels of eosinophils in the blood, a high erythrocyte sedimentation rate, iron deficiency anemia, and increased platelets. A chest X-ray can show abnormalities anywhere, but the most specific finding is increased shadow in the periphery of the lungs, away from the heart.
Eosinophilia, increase (>500 cells per microliter) in eosinophil blood count Hypereosinophilia , extreme increase (>1,500 cells per microliter) in eosinophil blood count Clonal hypereosinophilia , presence of a premalignant or malignant clone of eosinophils in bone marrow and blood
In 1987, however, a 42-year-old male patient was described who presented with cardiac failure, mitral heart valve regurgitation, pericardial effusion, splenomegaly, kidney dysfunction, non-specific skin lesions, a six-year history of eosinophilia, and, on admission, an eosinophil blood count of 7,150 per microliter (normal <500/microliter), a ...
Typically, the disorder is associated with hypereosinophilia, i.e. an eosinophil blood cell count greater than 1,500 per microliter (normal 100 to 400 per microliter). It is distinguished from non-eosinophilic myocarditis , which is heart inflammation caused by other types of white blood cells, i.e. lymphocytes and monocytes , as well as the ...
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Eosinophilic pneumonia is diagnosed by characteristic imaging and the presence of eosinophils on alveolar lavage, or washing of the lower respiratory system. Eosinophilia, or elevated eosinophils in the blood may be significantly elevated or absent. [3] Lung biopsy is usually not necessary for diagnosis. [3]
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