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Sodium thiosulfate is a classical antidote to cyanide poisoning, [10] For this purpose it is used after the medication sodium nitrite and typically only recommended for severe cases. [4] [6] It is given by injection into a vein. [4] In this use, sodium nitrite creates methemoglobinemia which removes cyanide from mitochondria. [6]
The evidence for sodium thiosulfate's use is based on animal studies and case reports: the small quantities of cyanide present in dietary sources and in cigarette smoke are normally metabolized to relatively harmless thiocyanate by the mitochondrial enzyme rhodanese (thiosulfate cyanide sulfurtransferase), which uses thiosulfate as a substrate ...
Sodium thiosulfate (sodium thiosulphate) is an inorganic compound with the formula Na 2 S 2 O 3 ·(H 2 O) x. Typically it is available as the white or colorless pentahydrate (x = 5), which is a white solid that dissolves well in water.
March 11, 2020: Zachary Sabin, an 11-year-old child, died after being forced to drink almost three liters of water in just four hours by his parents. They thought his urine was too dark, so they made him drink water until he threw up. [26] A 2022 study proposed that martial-arts actor Bruce Lee's death in 1973 was due to water poisoning. [27]
The related sodium thiosulfate also dechlorinates water. Campden tablets are also useful for decontamination and neutralization after exposure to tear gas. [4] The molar mass (commonly called molecular weight or MW) of potassium metabisulfite is 222 g/mol, and that of sodium metabisulfite is 190 g/mol.
You may need to increase your sodium intake if you are sweating a lot, such as when working out or on a hot day. “Sodium is an electrolyte needed for balanced fluid and blood volume and ...
This chemical is commonly handled as a dilute aqueous solution. It is used as an alternative to chlorine and sodium hypochlorite for disinfection of drinking water and swimming pools. Chloramine-T, or tosylchloramide sodium salt, [(H 3 C)(C 6 H 4)(SO 2)(NHCl)] − Na +. This solid compound is available in tablet or powder form, and used in ...
Sodium nitrite/sodium thiosulfate, sold under the brand name Nithiodote, is a fixed-dose combination medication used as an antidote for cyanide poisoning. [1] It contains sodium thiosulfate and sodium nitrite. [1] It is given by intravenous infusion into a vein. [1] It was approved for medical use in the United States in January 2011. [2]