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Caffeine's biological half-life – the time required for the body to eliminate one-half of a dose – varies widely among individuals according to factors such as pregnancy, other drugs, liver enzyme function level (needed for caffeine metabolism) and age.
Research indicates that caffeine, ingested either by drinking coffee or by taking a caffeine supplement, can help improve memory, explains Brynna Connor, M.D. “There is also evidence that shows ...
The health effects of coffee include various possible health benefits and health risks. [1]A 2017 umbrella review of meta-analyses found that drinking coffee is generally safe within usual levels of intake and is more likely to improve health outcomes than to cause harm at doses of 3 or 4 cups of coffee daily.
A number of fatalities have been caused by overdoses of readily available powdered caffeine supplements, for which the estimated lethal amount is less than a tablespoon. [13] The lethal dose is lower in individuals whose ability to metabolize caffeine is impaired due to genetics or chronic liver disease. [14]
A new study has found that consuming 6 milligrams of the coffee compound cafestol twice daily for 12 weeks might help reduce weight and body fat but not improve insulin sensitivity or glucose ...
Fatty liver disease happens when fat builds up in your liver. This can cause damage, inflammation, and other complications. ... If you get a liver function test for another reason, your healthcare ...
Paraxanthine is the primary metabolite of caffeine in humans and other animals, such as mice. [3] Shortly after ingestion, roughly 84% of caffeine is metabolized into paraxanthine by hepatic cytochrome P450, which removes a methyl group from the N3 position of caffeine.
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